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Calebin A 98% CAS 336784-82-8 | High-Purity Curcuminoid Supplier & Manufacturer
Calebin A (CAS: 336784-82-8) is a naturally occurring curcuminoid analog primarily isolated from Curcuma longa (turmeric) in the Zingiberaceae family. Structurally related to curcumin, Calebin A features a unique feruloylmethyl ester linkage that enhances its chemical stability and bioavailability compared to conventional curcuminoids.
Product Name :
Calebin ACAS No. :
336784-82-8Appearance :
Yellow to orange crystalline powderSpecification :
98%
Product Name: Calebin A
Synonyms: Curcuminoid analog, Natural curcumin derivative, Polyphenolic compound
CAS Number: 336784-82-8
Molecular Formula: C??H??O?
Molecular Weight: 384.38 g/mol
Appearance: Yellow to orange crystalline powder
Source: Extracted from Curcuma longa (Turmeric)
Category: Natural curcuminoid / Polyphenol compound / Bioactive phytochemical
Calebin A (CAS: 336784-82-8) is a naturally occurring curcuminoid analog isolated from Curcuma longa (turmeric), belonging to the family Zingiberaceae. It is structurally related to curcumin but distinguished by the presence of a unique feruloylmethyl ester linkage that enhances its biological stability and bioavailability.
As a polyphenolic compound, Calebin A exhibits a diverse range of biological activities, including anti-inflammatory, antioxidant, anticancer, and neuroprotective effects. It has been increasingly recognized as a promising molecule in pharmaceutical, nutraceutical, and biomedical research.
In pharmacological studies, Calebin A has demonstrated the ability to modulate NF-κB and STAT3 signaling pathways, inhibit inflammatory mediators such as COX-2 and TNF-α, and promote apoptosis in tumor cells. Its potent ROS-scavenging capacity and cytoprotective functions make it a valuable research tool in exploring chronic inflammation, oxidative stress, and degenerative disease mechanisms.
Calebin A is also widely studied for its potential role in chemoprevention, metabolic health, and brain protection, offering unique advantages over conventional curcuminoids due to its improved chemical stability and cellular permeability.
We supply ≥98% high-purity Calebin A with complete analytical documentation (COA, HPLC, MS, NMR) to support reproducible and reliable scientific research applications.
?? High Purity: ≥98% verified by HPLC – ideal for biochemical, pharmaceutical, and academic research
?? Natural Origin: Extracted and refined from Curcuma longa root-derived curcuminoids
?? Potent Bioactivity: Exhibits antioxidant, anti-inflammatory, and anticancer properties
?? Research Grade: Suitable for use in cell culture, pharmacological, and molecular biology studies
?? Full Analytical Support: COA, HPLC chromatograms, MS, and NMR spectra available on request
Pharmaceutical Research: Investigated for potential applications in anticancer, anti-inflammatory, and neuroprotective therapies
Signal Transduction Studies: Used to study NF-κB, STAT3, and MAPK signaling modulation
Antioxidant Mechanism Research: Applied in oxidative stress, redox biology, and cellular protection models
Nutraceutical & Functional Food Research: Potential bioactive ingredient for dietary supplement formulation
Biomedical Studies: Utilized in inflammation, apoptosis, and metabolic regulation research
| Property | Specification |
|---|---|
| Product Name | Calebin A |
| CAS Number | 336784-82-8 |
| Molecular Formula | C??H??O? |
| Molecular Weight | 384.38 g/mol |
| Appearance | Yellow to orange crystalline powder |
| Purity | ≥98% (HPLC) |
| Source | Curcuma longa extract |
| Solubility | Soluble in DMSO, ethanol, and methanol; poorly soluble in water |
| Storage | –20 °C, dry and protected from light |
| Shelf Life | 24 months under proper storage conditions |
All Calebin A batches are tested and verified through multiple analytical techniques to ensure identity, purity, and reproducibility.
HPLC Purity Analysis: Verified using high-performance liquid chromatography (HPLC) with UV detection; purity confirmed ≥98%.
Structural Identification: Confirmed by Mass Spectrometry (MS) and ¹H-NMR / ¹³C-NMR spectroscopy.
Spectral Characterization: UV-Vis and IR spectroscopy validate the polyphenolic and curcuminoid structural features.
Residual Solvent Analysis: Conducted per ICH Q3C standards to ensure trace solvent safety.
Moisture Content: ≤1.0%, tested by Karl Fischer titration.
Heavy Metals: ≤10 ppm (ICP-MS), meeting analytical-grade requirements.
Microbial Limit Test: Ensures the product is free from bacterial or fungal contamination.
Each order is supplied with a Certificate of Analysis (COA), HPLC chromatogram, MS, and NMR spectra to guarantee scientific traceability and reliability.
? Professional Manufacturer & Supplier – Specialized in natural curcuminoids and bioactive plant compounds
? Consistent High Quality – Verified by advanced analytical instruments (HPLC, MS, NMR)
? Flexible Quantities – From small research packs to bulk manufacturing scale
? Trusted by Global Researchers – Used in pharmaceutical, nutraceutical, and academic R&D labs
? Fast Worldwide Delivery – Secure packaging and temperature-controlled shipping
Standard Packaging: 1 mg, 5 mg, 10 mg, 25 mg
Bulk Packaging: Available upon request
Custom Packaging: Tailored options for specific research needs
All shipments are handled under controlled conditions to ensure product stability and safe international delivery.
Looking for high-purity Calebin A (CAS: 336784-82-8) for inflammation, oxidative stress, or cancer-related research?
We supply ≥98% research-grade Calebin A with full analytical documentation and expert technical support.
?? Website: www.km-origus.com.cn
?? Contact us today for quotations, samples, or detailed technical data sheets.
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