English
What Are You Looking For?
Glabridin: Nature’s Gold Standard for Multi-Action Skin Brightening & Antioxidant Defense
Derived from sustainably harvested Glycyrrhiza Glabra roots, Glabridin is a rare, naturally potent compound celebrated as "skin whitening gold" for its unparalleled ability to inhibit tyrosinase activity, disrupt melanin pathways, and visibly reduce hyperpigmentation
Product Name :
GlabridinCAS No. :
59870-68-7Appearance :
Off-white to pale yellow crystalline powderSpecification :
1%-98%CAS: 59870-68-7
Molecular Formula: C??H??O?
Molecular Weight: 324.37
Appearance: Off-white to pale yellow crystalline powder
Multi-Functional Skin Brightening & Anti-Aging Powerhouse
≥98% Pure: Cosmetic/Pharmaceutical Grade (HPLC-verified)
0.1%-5% Blends: Optimized for brightening serums, sun care, and age-reversal formulations
Tyrosinase Dual-Inhibitor: Unique mechanism blocking both monophenolase and diphenolase activity for superior melanin suppression
Hyperpigmentation Correction:
Reduces melanin synthesis by 56% at 0.4% concentration (vs. 22% for kojic acid), fading sun spots and melasma in 8 weeks with 91% user satisfaction (n=45).
Anti-Photoaging & UV Defense:
Blocks 95% of UVA-induced ROS at 2.0% concentration and boosts collagen IV synthesis by 40% to prevent solar elastosis.
Barrier Enhancement & Anti-Inflammation:
Increases ceramide synthesis by 35% and reduces TNF-α by 78%, calming sensitive skin and improving hydration retention.
Antioxidant Supercharger:
Exhibits 8× stronger free radical scavenging than vitamin E (ORAC: 28,000 μmol TE/g), neutralizing pollution and blue light damage.
| Parameter | Detail |
|---|---|
| Purity Range | 1%, 5%, 10%, 20%, 98%+ (HPLC-DAD) |
| Source | Glycyrrhiza glabra roots (Xinjiang, China - GACP certified) |
| Extraction Method | Ethanol/water → Macroporous resin → Prep-HPLC |
| Melting Point | 156–158°C |
| Solubility | Ethanol, PG, DMI; insoluble in water |
| Storage | -20°C in amber vials (36-month stability) |
| Key Impurities | Licochalcone A ≤0.2% (HPLC-controlled) |
| Certifications | ISO 22716, Halal, COSMOS-approved |
? Brightening & Even-Tone Serums:
Synergizes with niacinamide and tranexamic acid at 0.2–2.0% for 4× faster pigment fading than arbutin.
?? High-Performance Sun Care:
Critical in SPF 50+ formulations (1–4%) to prevent post-inflammatory hyperpigmentation and repair UV DNA damage.
??♀? Anti-Aging & Firming Creams:
Combined with retinol and peptides, reduces wrinkle depth by 42% in 12 weeks via MMP-1 inhibition and elastin stimulation.
?? Sensitive Skin Solutions:
At 0.5%, calms rosacea redness by 65% and strengthens barrier function in CBD-infused moisturizers.
?? Bioactivity-Preserving Extraction:
CO? Supercritical Extraction: Yields 92% glabridin vs. 50% ethanol methods, preserving heat-sensitive flavonoids.
3-Stage Chromatography: HPD-600 resin → Sephadex LH-20 → Prep-HPLC for >98% purity.
?? Enhanced Delivery Systems:
Phytosome® Technology: 5.8× skin penetration boost vs. free glabridin (QTY: 4.3 μg/cm²).
?? Global Compliance:
China IECIC, EU Cosmetic Regulation 1223/2009, FDA OTC Monograph. Full cosmetic safety dossier available.
| Cargo Weight | Packaging Method | Shipping | Lead Time |
|---|---|---|---|
| 1–10 kg | Vacuum-sealed amber glass vials | Dry Ice FedEx | 5 days |
| 10–100 kg | Pharma-grade aluminum cans | Air freight | 7–12 days |
| >100 kg | Nitrogen-flushed palletized drums | Sea freight | 30–55 days |
How to verify glabridin potency?
Free 10g samples with dual-method COA (HPLC at λmax 282 nm + UPLC-MS/MS confirmation).
Compatible with vitamin C?
Yes—stabilizes L-ascorbic acid in serums (pH 3.5–4.5), enhancing brightening synergy by 120%.
Stability in anhydrous formulas?
Maintains >95% potency for 24 months in oil-based serums; protect from oxygen and light.
?? Sustainable & Traceable Sourcing:
Wild-simulated G. glabra from Xinjiang deserts (zero irrigation, 0 pesticide residues).
?? Formulation-Ready Solutions:
Custom derivatives:
Glabridin Palmitate: Oil-soluble for makeup products (log P 8.2 vs. native 3.7)
Glabridin-Hyaluronate Complex: Targeted delivery for melasma treatment
Bakuchiol (INCI: Bakuchiol), a revolutionary plant-derived skincare ingredient, is rapidly gaining global recognition as a natural alternative to retinol (Vitamin A). Extracted from the seeds of Psoralea corylifolia (Babchi plant), this golden-hued oil combines traditional herbal wisdom with cutting-edge biotechnology. Recognized for its multifunctional anti-aging properties and gentle nature, bakuchiol is ideal for sensitive, acne-prone, or retinoid-intolerant skin .
Read More
Ectoin 98% is a premium cosmetic-grade active derived from Halomonas elongata via sustainable bio-fermentation, offering unparalleled protection against environmental stressors. Clinically proven to reduce transepidermal water loss by 32% and repair UV-induced DNA damage by 80–90% at 4.0% concentration, it forms a "hydration shell" to lock in moisture and shield skin from pollution, blue light, and inflammation.
Read More
Derived from sustainably harvested Glycyrrhiza Glabra roots, Glabridin is a rare, naturally potent compound celebrated as "skin whitening gold" for its unparalleled ability to inhibit tyrosinase activity, disrupt melanin pathways, and visibly reduce hyperpigmentation
Read More
Derived from licorice roots (Glycyrrhiza glabra) via optimized ethanol/water extraction, Isoliquiritigenin is a high-purity (99%) flavonoid renowned for its potent antioxidant and anti-inflammatory properties, validated in both in vitro and in vivo studies
Read More
Liquiritigenin (CAS 578-86-9) is a bioactive dihydroflavone predominantly isolated from Glycyrrhiza uralensis (licorice root). As a key marker compound in traditional Chinese medicine, it demonstrates potent antioxidant, anti-inflammatory, and phytoestrogenic properties.
Read More
Phloretin, with a purity of 98%, is a high - quality plant extract derived from the peels and root barks of apples.It has extremely strong antioxidant properties. It can inhibit the disordered proliferation of cells and serves as an anti - mutagenic factor in food. It shows potential as a chemotherapy drug and can be used in the treatment of skin cancer and other tumors.
Read More
Gentiopicroside 98% (CAS: 20831-76-9) is a premium bioactive extracted from Gentiana scabra roots, clinically proven to disrupt skin inflammation at the molecular level. This HPLC-validated crystalline powder (≥98% purity, λmax 270 nm) targets TNF-α/NF-κB pathways, delivering.
Read More
High-quality Licochalcone A 20% from Glycyrrhiza inflata. Ideal for cosmetics and skin care, offering anti-inflammatory, antioxidant, and soothing benefits.
Read More
Premium Licochalcone A 98% (CAS 58749-22-7) with ≥98% HPLC purity. Reliable supplier for pharmaceutical, nutraceutical, and biomedical research.
Read More
IPv6 network supported